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ST. LOUIS (2-9) At SAN FRANCISCO (9-2)
Sunday, 4:15 p.m., Fox
OPENING LINE - 49ers by 13
RECORD VS. SPREAD - St. Louis 2-9; San Francisco 9-1-1
SERIES RECORD - Rams lead 61-60-2
LAST MEETING - Rams beat 49ers 25-17, Dec. 27, 2010
LAST WEEK - Rams lost to Cardinals 23-20; 49ers lost to Ravens 16-6
RAMS OFFENSE - OVERALL (29), RUSH (21), PASS (26)
RAMS DEFENSE - OVERALL (21), RUSH (32), PASS (8)
49ERS OFFENSE - OVERALL (26), RUSH (7), PASS (29)
49ERS DEFENSE - OVERALL (7), RUSH (1), PASS (21)
STREAKS, STATS AND NOTES - 49ers had won five straight before losing at St. Louis in second-to-last week of 2010 season. After that game, coach Mike Singletary was fired, which led to hiring of Jim Harbaugh in January. … Harbaugh would join George Seifert (1989) and Steve Mariucci (1997) as only rookie coaches in franchise history to win NFC West in first year. … Niners are unbeaten in last nine home games vs. NFC West. … Nick Miller’s 88-yard punt return for TD last week against Arizona was Rams’ first since 85-yarder by Dante Hall on Sept. 30, 2007 at Dallas. … Rams’ last-place run defense allowed Cardinals’ Beanie Wells to set franchise mark with 228 yards rushing on 27 carries - St. Louis’ second time this year giving up a career day to an opponent. Rams also allowed 253 yards to Dallas’ DeMarco Murray in Week 6. … Over last eight games, 49ers defense has held opponents to seven TDs in 20 red-zone possessions. … San Francisco’s current 11-game streak without allowing rushing TD ranks tied for first in NFL since 1970 for most consecutive games not allowing rushing TD at any point in a single season. … RB Frank Gore (7,323) needs 22 yards rushing to pass late Hall of Famer Joe Perry (7,344) for most in franchise history. … 49ers defense has not allowed TD in first half in each of past five games, which is longest streak in franchise history and most in NFL since Dallas Cowboys had five consecutive games doing so in 2008.